Gene marker may improve odds of stem cell therapies for disease
A single tumor-suppressor gene may provide a unique marker for senescence in Mesenchymal stem cells (MSCs) in vitro, while also playing a role in moving MSCs into senescence, researchers at the Human Health Foundation and the Sbarro Institute for Cancer Research and Molecular Medicine report.
Their work was published in Stem Cells and Development .
The finding is important, since MSCs are currently being tested in cell and gene therapy for a number of human diseases.
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