(Ivanhoe Newswire) — Scientists have uncovered a genetic “fingerprint” to help predict whether a patient’s liver cancer will return after treatment.
A team of international researchers studied tissue samples of roughly 300 liver cancer patients to uncover more than 180 genes linked to patient survival. Interestingly, the predictive fingerprint was discovered not in the tumor, but in normal tissue surrounding it.
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WEDNESDAY, Oct. 15 — Researchers have identified a new genetic signature that may predict whether a liver tumor is likely to recur, according to a new study.
Unlike other such signatures that have been identified for other cancers, this one has something of a flourish: It is hidden not within the tumor itself, but in the normal cells that surround it — and which, by inference, remain in the body following surgery.
The findings potentially open the door to new surveillance, treatment, and intervention strategies for liver cancer patients, both after surgery and possibly before the primary cancer ever arises, experts said.
NEW YORK (Reuters Health) - People who undergo liver transplantation, particularly children, are at increased risk for developing cancer, Finnish researchers report in the journal Liver Transplantation.
“On the basis of our data,” Dr. Fredrik Aberg, from the Helsinki University Central Hospital, and co-authors note, “1 of 6 liver transplant patients is estimated to develop some form of cancer by 20 years after transplantation.”