By Michael Kahn
LONDON (Reuters) - British scientists have figured out why some women develop resistance to the most commonly used breast cancer drug, something that raises the risk their tumors will return, according to a study published on Wednesday.
The findings could lead to new tests to determine which women are not likely to benefit from tamoxifen and who should be given other drugs, said Jason Carroll of Cancer Research UK in Cambridge, who led the study published in the journal Nature.
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January 12th, 2009 | Posted in Breast Cancer, News | Tags: breast, cancer, Drug, Resistance, scientists, Unravel
WEDNESDAY, Nov. 12 — As many as 35 percent of women who take tamoxifen to prevent the return of breast cancer do not respond to the drug — and now scientists think they know why.
A battle between proteins to turn a breast cancer gene off or on determines if tamoxifen works or not, the scientists report. The finding could be used to spot those women who won’t respond to the drug, and it may even lead to new therapies.
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January 6th, 2009 | Posted in Breast Cancer, News | Tags: mystery, Resistance, scientists, Tamoxifen, Unravel